The Seattle Seahawks vs Arizona Cardinals rivalry has always carried extra weight in the NFC West. Anytime these two teams face off, the stakes are more than just another regular-season game—it’s about divisional pride, playoff positioning, and bragging rights for some of the most passionate fan bases in the NFL.
Seattle enters this matchup with one of the league’s most dynamic offenses, while Arizona is trying to prove they can bounce back and make a serious run in the NFC. Fans searching for “how to watch Seahawks game live,” “Cardinals vs Seahawks predictions,” or “Thursday Night Football streaming” will find everything they need in this guide: kickoff time, TV broadcast details, betting odds, key player updates, and expert analysis.
With kickoff set for 8:15 PM ET tomorrow, let’s dive into everything you need to know before this primetime showdown.
Game Time & How to Watch Live
- Date: Thursday, September 25, 2025
- Kickoff Time: 8:15 PM ET (5:15 PM PT)
- Location: Lumen Field – Seattle, Washington
- Watch On TV: Amazon Prime Video (Thursday Night Football exclusive)
- Live Stream: Available via Prime Video app (U.S. only), NFL+ (mobile), and select international broadcasters.
👉 Many fans search “Seahawks vs Cardinals live stream free” or “TNF how to watch without cable”. The only legal U.S. streaming option is Amazon Prime Video. International viewers can check their local NFL broadcast partners.
Current Odds & Betting Lines
Sportsbooks have the Seahawks favored at -4.5, with the over/under set at 46.5 points.
- Moneyline: Seahawks -190 | Cardinals +160
- Spread: Seahawks -4.5
- Total: 46.5
Bettors looking for “Seahawks vs Cardinals betting picks” should note Seattle has covered the spread in 4 of their last 5 divisional games. Meanwhile, Arizona has struggled against NFC West opponents on the road.
Key Storylines
1. Geno Smith’s Consistency
Seattle’s quarterback has been one of the most accurate passers in the NFL this season. Fans searching “Is Geno Smith elite?” will be watching closely to see if he continues to protect the football and make big plays downfield.
2. Cardinals’ Young Defense
Arizona’s defense is loaded with rookies and second-year players. The big question: can they slow down Seattle’s receiving duo of DK Metcalf and Tyler Lockett?
3. NFC West Race
Every divisional win counts. With the 49ers leading the West, both Seattle and Arizona know that dropping this primetime game could mean falling behind in the playoff chase.
Injuries & Player Updates
- Seahawks: RB Kenneth Walker (questionable), LT Charles Cross (probable).
- Cardinals: QB Kyler Murray (probable), WR Marquise “Hollywood” Brown (questionable).
Fantasy football players searching “Seahawks vs Cardinals fantasy start sit” should track injury reports up until kickoff.
Head-to-Head History
The Seahawks lead the all-time series 26–23–1. Recent meetings have been split, with each team winning once last season. Historically, Seattle has dominated at home in Lumen Field, where the crowd noise is among the loudest in the NFL.
Prediction: Who Wins?
This game has all the makings of a classic NFC West battle. Seattle’s offense looks sharper and their home-field advantage is real. Arizona’s young defense will make plays, but Geno Smith’s poise should be the difference.
Predicted Score: Seahawks 27 – Cardinals 21
Expect a tight game that stays close into the fourth quarter before Seattle pulls away late.
Final Thoughts
The Seattle Seahawks vs Arizona Cardinals matchup isn’t just another Thursday Night Football broadcast—it’s a critical divisional game that could shape the NFC playoff race. Whether you’re searching for “how to watch Seahawks game tonight,” “Cardinals live stream,” or “NFL betting picks,” this game delivers everything fans love about primetime football.
Get your snacks ready, log into Prime Video, and prepare for another wild night of NFL action.